Eosinophilic stomatitis and eosoniphilic granuloma are common names associated with raised ulcerative oral lesions in dogs mainly associated with the palate and occassionally the tongue. The Cavalier King Charles Spaniel is particularly susceptable. Antigenic stimulation is thought to be the cause however often specific etiology cannot be determined. This Cavalier had both eosinophilic stomatitis and CUPS. The CUPS appeared to be the painful component in this patient and is a consistent component of most if not all cases of CUPS.

Eliminating the plaque with strict home care including brushing daily, and water additives to reduce plaque (Healthy Mouth) along with frequent prophy’s in the hospital (generally every 3 months) is the only safe treatment for CUPS. Immunosuppressive therapy is an alternative but potentially dangerous approach to therapy. Extracting the teeth adjacent to the lesions is the only definitive curative therapy.

Biopsy is indicated to confirm eosinophilic stomatitis. Treatment involves corticosteroids or cyclosporin and some have advocated hypoallergenic foods. Some patients do not respond to any of the above recommendations. A determination must be made to assess patient pain. Some of these patients appear not to be painful, however careful evaluation is needed to determine oral pain for this condition in dogs. Palpation under light sedation may reveal jaw chattering.